To administer a third vial, a new device must be opened. Polyaldehyde treated tissue can have an enhanced propensity for mineralization. Note how the cap attaches and detaches, since the delivery tip is attached in the same manner. Hold the syringe by the barrel, cap end upward. To prevent contamination the device or its accessory must not be reused.
Depending on where they occur, clots can lead to a stroke or heart attack. Align the tab in the notch, and push delivery tip into place.
Important Risk Information Not for use in patients with known allergies to materials of bovine or shellfish origin. Only use RaplixaSpray accessories. Allergic type hypersensitivity reactions may occur. Not for cerebrovascular repair or cerebrospinal leak repair. Warnings and Precautions For topical use only.
Avoid contact with skin or other tissue not intended for application. The use of accessories of other manufacturers is not permitted.
Mallinckrodt Hemostat Solutions
Warnings and Precautions Do not use as a substitute for sutures or staples. Do not cut the nozzle to length. Avoid pausing more than seconds between priming and application to prevent polymerization within the delivery tip. Apply the sealant in a slow and steady manner over the top of the suture line with the delivery tip approximating the sutures. Do not use in the presence of obvious infection and use with caution in contaminated areas of the body.
Air or gas embolism has occurred with the use of spray devices employing pressure regulators to administer fibrin sealants. Other brands are trademarks of a Mallinckrodt company or their respective owners. Air or gas embolism can occur using air- or gas-pressurized sprayers to administer fibrin sealants. The accessory, the flexible nozzle, is intended to enable the RaplixaSpray device to be used in difficult to reach areas. Rely on Mallinckrodt Hemostat Solutions.
Important Risk Information Do not apply intravascularly. Hypersensitivity reactions, including anaphylaxis, may occur. Open the outer pouch and place the inner sterile pouch onto the sterile field.
Do not use if packages have been opened or damaged. When this experimental drug was given to mice, the rodents showed slower blood clot formation, yet they also did not bleed longer than untreated mice, Tseng and her colleagues found. Do not manipulate the synthetic graft or patch. Do not allow either the uncured or polymerized form to contact circulating blood. Prior to restoring circulation, carefully use blunt dissection to ease away any sealant attached to the clamps.
The drug has yet to be tested in humans. Clinical evaluation report for ArterX Surgical Sealant. There is the potential for powder loss from the nozzle tip during or after usage. Ultimately, he and his colleagues hope their work could yield an entire class of effective antiplatelet drugs with limited side effects.
Safety and efficacy have not been established in neonates. Minimize use in patients with abnormal calcium metabolism e. Be careful not to push the RaplixaSpray device operating button when handing the device to the surgeon. Avoid tissue contact with material expelled from delivery tip during priming. Important Risk Information Do not inject directly into the circulatory system.
Do not use in patients with known hypersensitivity to hamster proteins. Because many drugs are excreted in human milk, caution should be exercised when administering to a nursing woman.
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